Neuropsychiatric Features of a Cohort of Patients with Systemic Lupus Erythematosus
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چکیده
منابع مشابه
Neuropsychiatric Features of a Cohort of Patients with Systemic Lupus Erythematosus
In order to establish if neuropsychiatric systemic lupus erythematosus (NPSLE) can be identified by any characteristic other than those used to diagnose the neuropsychiatric (NP) disease itself, we retrospectively reviewed 98 systemic lupus erythematosus (SLE) patients followed over a mean period of 10 years. NPSLE was identified in 22 patients. Stroke and generalized seizures were the most fre...
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Neuropsychiatric systemic lupus erythematosus (NPSLE) is the least understood, yet perhaps the most prevalent manifestation of lupus. The pathogenesis of NPSLE is multifactorial and involves various inflammatory cytokines, autoantibodies, and immune complexes resulting in vasculopathic, cytotoxic and autoantibody-mediated neuronal injury. The management of NPSLE is multimodal and has not been s...
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Background: Due to infections, cardio-vascular involvement and renal insufficiency, patients with systemic lupus erythematosus live shorter than usual. Objective: To determine the mean survival rate of SLE patients. Patients and Methods: 62 SLE patients admitted in the hospitals of Kerman University of Medical Sciences from 1369 to 1380 were included in this study. The demographic variabl...
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Neuropsychiatric (NP) involvement is a prevalent and often severe feature of Systemic Lupus Erythematosus (SLE). Diverse factors are involved in its aetiopathogenesis and treating this condition is often quite challenging. However, clinical trials of biologic therapies in patients with SLE exclude those with severe NP manifestations. The place for the use of biologic approaches is thus even mor...
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ژورنال
عنوان ژورنال: ISRN Rheumatology
سال: 2012
ISSN: 2090-5475
DOI: 10.5402/2012/989218